Workflows

The workflow starts with selecting atrial fibrillation as the search term. The workflow starts with selecting Ibrutinib as the search term. Gene sets with set labels containing atrial fibrillation were queried from Enrichr[1]. Identified matching terms from the MGI Mammalian Phenotype Level 4 2021[2] library were assembled into a collection of gene sets. A GMT was extracted from the Enrichr results for MGI_Mammalian_Phenotype_Level_4_2021. A consensus gene set was created by only retaining genes ...

The workflow starts with selecting Inflammation as the search term. The workflow starts with selecting Penicillin as the search term. The workflow starts with selecting Cortisol as the search term. Gene sets with set labels containing Inflammation were queried from Enrichr[1]. Identified matching terms from the GWAS Catalog 2019[2] library were assembled into a collection of gene sets. A GMT was extracted from the Enrichr results for GWAS_Catalog_2019. All the identified gene sets were combined ...

The input to this workflow is a data matrix of gene expression that was collected from a pediatric patient tumor patient from the KidsFirst Common Fund program [1]. The RNA-seq samples are the columns of the matrix, and the rows are the raw expression gene count for all human coding genes (Table 1). This data matrix is fed into TargetRanger [2] to screen for targets which are highly expressed in the tumor but lowly expressed across most healthy human tissues based on gene expression data collected ...