Workflows
What is a Workflow?Filters
Summary
The validation process proposed has two pipelines for filtering PPIs predicted by some IN SILICO detection method, both pipelines can be executed separately. The first pipeline (i) filter according to association rules of cellular locations extracted from HINT database. The second pipeline (ii) filter according to scientific papers where both proteins in the PPIs appear in interaction context in the sentences.
The pipeline (i) starts extracting cellular component annotations from ...
Summary
PredPrIn is a scientific workflow to predict Protein-Protein Interactions (PPIs) using machine learning to combine multiple PPI detection methods of proteins according to three categories: structural, based on primary aminoacid sequence and functional annotations.
PredPrIn contains three main steps: (i) acquirement and treatment of protein information, (ii) feature generation, and (iii) classification and analysis.
(i) The first step builds a knowledge base with the available annotations ...