The Laboratory of Systems and Synthetic Biology (SSB) contributes to elucidate mechanisms underlying basic cellular processes, evolution and interactions among microbes and between microbes and their environment (including the human host). We do so in the context of entire biological systems. We translate the acquired knowledge into biotechnological, medical and environmental applications.

galaxy-SynBioCAD is an open access Galaxy workflow environment to design and build different metabolic routes for the production of a compound of interest. Galaxy-SynBioCAD combines the proven efficiency of RetroPath2.0 and automated script generator to drive robotized workstations for vector assembly and strain transformation.

The workflow runs the RetroSynthesis algorithm to generate a collection of heterologous pathways in a host organism of choice, converts them to SBML files, performs analysis on the pathways to then rank the theoretical best performing ones.

Generate possible metabolic routes for the production of a target molecule in an organism of choice