This workflow runs 3 comparisons using MuSiC Deconvolution compare: where datasets cell compositions are inferred from a reference containing healthy and diseased cells; where diseased are inferred from disease and healthy from healthy; and where both diseased and healthy are inferred from a healthy reference.
Associated Tutorial
This workflows is part of the tutorial Comparing inferred cell compositions using MuSiC deconvolution, available in the GTN
Thanks to...
Workflow Author(s): Wendi Bacon, Mehmet Tekman
Tutorial Author(s): Wendi Bacon, Mehmet Tekman
Tutorial Contributor(s): Marisa Loach, Mehmet Tekman, Saskia Hiltemann, Wendi Bacon, Helena Rasche, Carlos Chee Mendonça, Morgan Howells, Björn Grüning
Inputs
| ID | Name | Description | Type | 
|---|---|---|---|
| ESet Object - Bulk:T2D | #main/ESet Object - Bulk:T2D | n/a | 
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| ESet Object - Bulk:normal | #main/ESet Object - Bulk:normal | n/a | 
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| ESet Object - Single cell Total | #main/ESet Object - Single cell Total | n/a | 
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| ESet Object - Single cell:T2D | #main/ESet Object - Single cell:T2D | n/a | 
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| ESet Object - Single cell:normal | #main/ESet Object - Single cell:normal | n/a | 
 | 
Steps
| ID | Name | Description | 
|---|---|---|
| 5 | MuSiC Compare: Like with like | Here the T2D bulk sample is inferred from the sc T2D sample, while the normal bulk sample is inferred from the sc normal sample toolshed.g2.bx.psu.edu/repos/bgruening/music_compare/music_compare/0.1.1+galaxy4 | 
| 6 | MuSiC Compare: healthyscref | Here the T2D bulk sample and the normal sample are separately compared separately against the healthy sc reference only (excluding unhealthy sc reference) toolshed.g2.bx.psu.edu/repos/bgruening/music_compare/music_compare/0.1.1+galaxy4 | 
| 7 | MuSiC Compare - Altogether | toolshed.g2.bx.psu.edu/repos/bgruening/music_compare/music_compare/0.1.1+galaxy4 | 
Outputs
| ID | Name | Description | Type | 
|---|---|---|---|
| _anonymous_output_1 | #main/_anonymous_output_1 | n/a | 
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| _anonymous_output_10 | #main/_anonymous_output_10 | n/a | 
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| _anonymous_output_11 | #main/_anonymous_output_11 | n/a | 
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| _anonymous_output_12 | #main/_anonymous_output_12 | n/a | 
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| _anonymous_output_2 | #main/_anonymous_output_2 | n/a | 
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| _anonymous_output_3 | #main/_anonymous_output_3 | n/a | 
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| _anonymous_output_4 | #main/_anonymous_output_4 | n/a | 
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| _anonymous_output_5 | #main/_anonymous_output_5 | n/a | 
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| _anonymous_output_6 | #main/_anonymous_output_6 | n/a | 
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| _anonymous_output_7 | #main/_anonymous_output_7 | n/a | 
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| _anonymous_output_8 | #main/_anonymous_output_8 | n/a | 
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| _anonymous_output_9 | #main/_anonymous_output_9 | n/a | 
 | 
Version History
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Views: 1143 Downloads: 159 Runs: 0
Created: 2nd Jun 2025 at 10:55
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