Workflows
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EXCON (v2.3.1)
A Nextflow pipeline for gene family EXpansion and CONtraction analysis across multiple species using CAFE5.
Given a set of genome assemblies and annotations, EXCON builds orthogroups with OrthoFinder, fits and compares multiple CAFE models to identify gene families evolving at significantly different rates, and automatically selects the best-fitting model for downstream analysis. Optionally, GO enrichment analysis can be run on expanded and contracted gene families, and ...
Using:
- vadr annotation (model to select)
- vardict variant caller
- coverage depth
Provides summarizing files:
- png image of variant calling with annotations and coverage depths
- tsv file with all information of significant variants only
- vcf file with all information of significant variants only (to allow downstream NextStrain analyses)
Type: Galaxy
Creators: Fabrice Touzain, This study was founded by the French National Research Agency and by Santé publique France as part of the project "EMERGEN". Anses Ploufragan research was also supported by Agglomération de Saint-Brieuc, Département des Côtes d'Armor and Région Bretagne
Submitter: Fabrice Touzain
Using:
- vadr annotation (model to select)
- vardict variant caller
- coverage depth
Provides summarizing files:
- png image of variant calling with annotations and coverage depths
- tsv file with all information of significant variants only
- vcf file with all information of significant variants only (to allow downstream NextStrain analyses)
Type: Galaxy
Creators: Fabrice Touzain, This study was founded by the French National Research Agency and by Santé publique France as part of the project "EMERGEN". Anses Ploufragan research was also supported by Agglomération de Saint-Brieuc, Département des Côtes d'Armor and Région Bretagne
Submitter: Fabrice Touzain
Using:
- vadr annotation (model to select)
- vardict variant caller
- coverage depth
Provides summarizing files:
- png image of variant calling with annotations and coverage depths
- tsv file with all information of significant variants only
- vcf file with all information of significant variants only (to allow downstream NextStrain analyses)
Type: Galaxy
Creators: Fabrice Touzain, This study was founded by the French National Research Agency and by Santé publique France as part of the project "EMERGEN". Anses Ploufragan research was also supported by Agglomération de Saint-Brieuc, Département des Côtes d'Armor and Région Bretagne
Submitter: Fabrice Touzain
Using:
- vadr annotation (model to select)
- vardict variant caller
- coverage depth
Provides summarizing files:
- png image of variant calling with annotations and coverage depths
- tsv file with all information of significant variants only
- vcf file with all information of significant variants only (to allow downstream NextStrain analyses)
Type: Galaxy
Creators: Fabrice Touzain, This study was founded by the French National Research Agency and by Santé publique France as part of the project "EMERGEN". Anses Ploufragan research was also supported by Agglomération de Saint-Brieuc, Département des Côtes d'Armor and Région Bretagne
Submitter: Fabrice Touzain
CMIP tutorial using BioExcel Building Blocks (biobb)
This tutorial aims to illustrate the process of computing classical molecular interaction potentials from protein structures, step by step, using the BioExcel Building Blocks library (biobb). Examples shown are Molecular Interaction Potentials (MIPs) grids, protein-protein/ligand interaction potentials, and protein titration. The particular structures used are the Lysozyme protein (PDB code 1AKI), ...
CMIP tutorial using BioExcel Building Blocks (biobb)
This tutorial aims to illustrate the process of computing classical molecular interaction potentials from protein structures, step by step, using the BioExcel Building Blocks library (biobb). Examples shown are Molecular Interaction Potentials (MIPs) grids, protein-protein/ligand interaction potentials, and protein titration. The particular structures used are the Lysozyme protein (PDB code 1AKI), ...
Train and evaluate a HANCOCK recurrence model with Multimodal Learner
Associated Tutorial
This workflows is part of the tutorial Gleam Multimodal Learner - Head and Neck cancer Recurrence Prediction with HANCOCK, available in the GTN
Features
- Includes Galaxy Workflow Tests ...
Automatic Ligand parameterization tutorial using BioExcel Building Blocks (biobb)
This tutorial aims to illustrate the process of ligand parameterization for a small molecule, step by step, using the BioExcel Building Blocks library (biobb). The particular example used is the Sulfasalazine protein (3-letter code SAS), used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease.
OpenBabel and ACPype packages are used to **add hydrogens, energetically ...
iPSC Data Analysis
Description
This project is part of the Dutch X-omics initiative and focuses on the analysis of multi-omics data from several iPSC lines. The data included genomics, transcriptomics, proteomics, and several different types of metabolomics.
Goal
The goal is to identify disease-specific traits of the patient-derived iPSC compared to various control lines.
Pipeline overview
File outline
|- README.md # This readme\ |- Data analysis plan.md ...